This is a report on the first detection of the Papaya mealybug in Uganda, August 2021. The detection was supported by a survey initiated by the need to confirm the presence of the Mango Mealybug after it was reported in Rwanda in 2019. The survey was facilitated by the Food and Agricultural Organisation, Rome, Italy. Samples of fruits and leaves were collected from the Eastern, Western, Northern and South western parts of Uganda. The samples were sent for laboratory diagnosis and identification to the British Natural Museum, in the United Kingdom. Laboratory reports confirmed presence of the Papaya mealybug, Paracoccus marginatus. from samples collected from Mbale district in the Eastern region, which neighbours Kenya.